EPOS

European Paediatric Ophthalmological Society

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Papain ferment in treatment of ocular developments of systemic inflammatory diseases of the connective tissue

Aznauryan Igor¹, Balasanyan Viktorya^1
1Association of pediatric ophthalmology clinics "Yasny Vzor"

Introduction:Ocular developments of systemic inflammatory diseases of the connective tissue compose from 1 to 5%. Established localization of a pathological process, which influences vision, is the area of optical mediums and optic nerve sheath. Thus, the choice of a method of amputation of postinflammatory connective tissue accrementitions has primary significance when selecting the ways of treatment of these states. Methods:21 patients were observed with subacute type of optochiasmic arachnoidite and 13 patients with persistent vitreous opacities after rheumatic fever. The average age of patients was 10.8±1.5 years. Evaluation criteria of the state of vision before and after the treatment were: • vision accuracy • field of vision • visual evoked potentials • degree of optical and ultrasonic transparency of vitreous body Proteolytic ferment papain (papaya extract) was used for treatment. Papain was applied by endonasal electrophoresis in case of optochiasmic arachnoidite. Treatment of rheumatoid vitreous opacities was performed by transpalpebral electrophoresis method. Results:Normalization of visual evoked potentials and fields of vision was observed on 17 patients with optochiasmic arachnoidite. Vision accuracy was 0.7-1.0. In 9 cases the increase of vision accuracy to 0.7-0.8 and optical and ultrasonic transparency of vitreous body was observed on patients with rheumatoid vitreous opacities. Conclusion:papain ferment effectively resolves pathological postinflammatory connective tissue accrementitions. In treatment of the above mentioned states in ophthalmology the treatment efficiency depends on the way the medicine is administered and on the phase of disease.