EPOS

European Paediatric Ophthalmological Society

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Choroidal Neovascularisation in an adolescent previously treated for nasopharyngeal carcinoma

Bilkiewicz-Pawelec Anna Maria¹, Uppal Gurmit S¹, Sumramanian Sujatha¹, Leitch Jane¹, Fison Peter^1
1The Roy Harfitt Eye Unit, Epsom and St.Helier University Hospitals NHS Trust, Sutton, UK

Introduction:A seventeen-year-old male presented to the eye casualty with a two-week history of blurred central vision in the right eye. The patient had a history of nasopharyngeal carcinoma diagnosed at age twelve which was treated with chemotherapy and radiotherapy. He had required right cataract extraction and intraocular lens implantation at age fourteen for a radiation induced posterior sub capsular cataract. Methods:Ocular examination revealed the visual acuity in the right eye as counting fingers and the left eye 6/9. Posterior segment examination of the right eye revealed a macular lesion suggestive of choroidal neovascularisation, with an epiretinal membrane and sub retinal fluid. This was imaged with fundus photography, fluorescein angiography and optical coherence tomography. Results:Treatment with an anti-VEGF is being considered and the outcome is to be closely observed. Conclusion:The mechanism of CNV development in ARMD and radiation retinopathy is compared.