EPOS

European Paediatric Ophthalmological Society

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OCT measurements in black and white children with large cup-to-disc ratios

El-Dairi Mays¹, Holgado Sandra¹, Asrani Sanjay¹, Freedman Sharon^1
1Duke Eye Center

Introduction: To evaluate optical coherence tomography (OCT) measurement of peripapillary retinal nerve fiber layer (RNFL) and macular thickness in black and white children who have a large cup-to-disc ratio (>0.6). Methods: The Stratus OCT was used to evaluated the peripapillary RNFL and macular thickness in normal children. Macular and RNFL thicknesses in children with large cup-to-disc ratio were compared against controls that were matched for age, race and gender. We included 81 pediatric subjects with a large cup-to-disc ratio (40 white, 41 black), and 81 normal controls (40 white, 41 black). Results: In white children, there was significant decrease in macular and RNFL thickness between those with a large cup-to-disc ratio and controls (Respectively, macular volume in mm³= 6.84 vs. 6.97, p=0.05, average RNFL thickness in µm= 99.56 vs. 107.88 p=0.0003). In black children, there was no statistical difference in the macular and RNFL thicknesses between those that had a large cup-to-disc ratio and controls. Conclusion: OCT shows decreased RNFL and macular thickness in white children with large cup-to-disc ratios. This difference, however, was not present in black children.